The San Francisco Giants (26–19) host the Oakland Athletics (22–23) tonight at Oracle Park in the second game of their "Highway 80" rivalry series. The Giants are coming off a dominant 9–1 victory in the series opener, highlighted by Wilmer Flores' historic three-home-run, eight-RBI performance. San Francisco has been strong at home, boasting a 14–7 record. The Athletics, meanwhile, have struggled recently, losing four of their last five games, including a 19–2 defeat to the Dodgers prior to this series.

San Francisco's offense ranks eighth in MLB, averaging 4.84 runs per game, and their pitching staff holds a 3.48 ERA, also eighth-best in the league. Wilmer Flores leads the team with a .266 batting average, 10 home runs, and 41 RBIs, tying him with Aaron Judge for the MLB lead in RBIs. On the mound, Landen Roupp (2–3, 4.95 ERA) will start for the Giants. While Roupp has faced challenges, he has pitched five or more innings in his last two starts, aiming to provide stability against an Athletics lineup that has been inconsistent.

The Athletics' pitching staff has struggled significantly, allowing a combined 37 runs over their last three games. Luis Severino (1–4, 4.70 ERA) will start for Oakland; he has had difficulty containing opposing offenses, giving up eight runs in his last start against the Yankees. The Giants' lineup, energized by Flores' recent performance, is poised to capitalize on these pitching woes. Additionally, San Francisco's bullpen has been reliable, providing support in late-game situations.

San Francisco has been successful against the spread, with a 24–21 record this season. They have also performed well as favorites, winning 64% of such games. In contrast, the Athletics have struggled as underdogs, winning only 37.9% of those games. Given these trends and the current form of both teams, the Giants are well-positioned to cover the -1.5 run line in tonight's matchup.

Best odds available at Bet365.